Traduction de «Indice de pathogénicité intracérébrale » (Français → Anglais) :

intracerebral pathogenicity index | ICPI [Abbr.]

intracerebral pathogenicity index | ICPI [Abbr.]

intracerebral pathogenicity index test

intravenous pathogenicity index

caused by any avian strain of the paramyxovirus 1 with an intracerebral pathogenicity index (ICPI) in day-old chicks greater than 0,7; or

multiple basic amino acids have been demonstrated in the virus (either directly or by deduction) at the C-terminus of the F2 protein and phenylalanine at residue 117, which is the N-terminus of the F1 protein; the term ‘multiple basic amino acids’ refers to at least three arginine or lysine residues between residues 113 and 116; failure to demonstrate the characteristic pattern of amino acid residues as described in this point requires characterisation of the isolated virus by an ICPI test; in this definition, amino acid residues are numbered from the N-terminus of the amino acid sequence deduced from the nucleotide sequence of the F0 ...[+++] gene, 113-116 corresponds to residues -4 to -1 from the cleavage site;

in which no avian paramyxoviruses with an Intracerebral Pathogenicity Index of more than 0,4 have been found.

Inactivated Newcastle disease vaccines shall be prepared from a Newcastle disease virus strain with an intracerebral pathogenicity index (ICPI) in one-day-old chicks of less than 0,7, if not less than 108 EID50 are administered to each bird in the ICPI test.